Hormone/Androgen-deprivation therapy (ADT)

(ADT) may be used in conjunction with radiation therapy if your cancer is more aggressive, with higher PSA, higher Gleason score, or if Prolaris results lean towards a more aggressive cancer. Male hormones, specifically testosterone, fuel the growth of prostate cancer. By reducing the amount and activity of testosterone, the growth of prostate cancer is slowed.

Hormone (endocrine) therapy, is also known as androgen ablation, androgen suppression therapy, or androgen deprivation therapy. This is given as an injection, either monthly, every three months, or every six months and anywhere from one injection to a total of two years of injections may be given. Possible side effects include hot flashes, decreased libido, and /or injection site tenderness. Hormone therapy is designed to reduce the levels of male hormones and starve the tumor.

  1. Leutenizing hormone (LH) is secreted by the pituitary gland which sends a signal to produce testosterone.
  2. LHRH agonists prevent the testicles from getting a signal to produce testosterone.
  3. Anti-androgens prevent the small amount of testosterone produced by adrenals.
  4. The reduction in hormones starves the tumor.

Questions About Intensity-Modulated Radiation Therapy and ADT Treatment?

For more information, please give our adult urology experts at Advanced Urology Associates a call at 815.409.4930 or request an appointment.