How are my cells Collected for PROVENGE Treatment?

Each dose of PROVENGE is made just for you. To make each dose, blood is drawn and flows through a tube to a machine that collects a small portion of immune cells from the blood sample. This process is called leukapheresis (pronounced loo-kuh-fuh-REE-sis). Before your first leukapheresis procedure, you will need a common blood test called a complete blood count (CBC). This test measures your blood-cell levels.

Your doctor will also check your veins to decide the best way for your blood to be drawn. This may be through a vein or through a central venous catheter, a thin, flexible tube placed into a large vein near the heart. If your doctor decides you need a central venous catheter, it will be kept in place for all of your blood draws
as well as each of your PROVENGE infusions.

How cells are collected for PROVENGE Advanced Cancer Treatment from Advanced Urology Associates

It will take about 3 to 4 hours for the entire leukapheresis procedure. Many patients like to listen to music or watch a movie during this time. Your procedure will take place at a blood center that has been trained to perform the leukapheresis procedure.

Some people may notice side effects when their cells are collected. These can include dizziness, fatigue, tingling in the fingers and around the mouth, feeling cold, fainting, and nausea. For more information, talk with your doctor.

Before Your Leukapheresis Procedure…

  • Make sure to drink more water than usual to stay well hydrated
  • Avoid drinking caffeinated beverages on the day of each leukapheresis procedure
  • Eat a calcium-rich breakfast, which may include yogurt, milk, calcium-fortified orange juice or cereal, bananas, blueberries, or almonds
  • Wear comfortable, loose-fitting clothing, especially clothing with sleeves that can be raised above the elbow
  • In general, most people feel fatigued after the leukapheresis procedure, so having an alternate driver for the ride home is recommended